| Date | Location | Result | |
| 03/15/21 | Canyon, TX | Lubbock Christian 78, Southwestern Okla. 65 | Box score |
| 03/13/21 | Canyon, TX | Southwestern Okla. 97, Tex. A&M-Commerce 79 | Box score |
| 03/05/21 | Weatherford, OK | Southern Nazarene 88, Southwestern Okla. 74 | Box score |
| 03/03/21 | Weatherford, OK | Southwestern Okla. 89, Ouachita Baptist 66 | Box score |
| 02/27/21 | Shawnee, OK | Southwestern Okla. 85, Okla. Baptist 71 | Box score |
| 02/25/21 | Weatherford, OK | Southwestern Okla. 71, Southern Nazarene 60 | Box score |
| 02/22/21 | Alva, OK | Southwestern Okla. 88, Northwestern Okla. 82 | Box score |
| 02/20/21 | Durant, OK | Southwestern Okla. 73, Southeastern Okla. 66 | Box score |
| 02/13/21 | Weatherford, OK | Southwestern Okla. 93, Okla. Baptist 64 | Box score |
| 02/11/21 | Bethany, OK | Southern Nazarene 73, Southwestern Okla. 63 | Box score |
| 02/06/21 | Ada, OK | Southwestern Okla. 93, East Central 63 | Box score |
| 02/04/21 | Weatherford, OK | Southwestern Okla. 74, Southeastern Okla. 67 | Box score |
| 01/30/21 | Weatherford, OK | Southwestern Okla. 91, Southern Nazarene 76 | Box score |
| 01/28/21 | Shawnee, OK | Southwestern Okla. 88, Okla. Baptist 64 | Box score |
| 01/25/21 | Alva, OK | Southwestern Okla. 87, Northwestern Okla. 77 | Box score |
| 01/23/21 | Weatherford, OK | East Central 85, Southwestern Okla. 75 | Box score |
| 01/21/21 | Durant, OK | Southwestern Okla. 77, Southeastern Okla. 67 | Box score |
| 01/16/21 | Weatherford, OK | Southwestern Okla. 91, Okla. Baptist 58 | Box score |
| 01/14/21 | Bethany, OK | Southwestern Okla. 98, Southern Nazarene 73 | Box score |
| 01/11/21 | Weatherford, OK | Southwestern Okla. 93, Northwestern Okla. 47 | Box score |
| 01/09/21 | Weatherford, OK | Southwestern Okla. 101, Southeastern Okla. 64 | Box score |
| 01/07/21 | Ada, OK | Southwestern Okla. 92, East Central 77 | Box score |