| Date | Location | Result | |
| Nov 11, 2000 | Wichita Falls, TX | Midwestern State 40, Southwestern Okla. 7 | |
| Nov 04, 2000 | Weatherford, Okla | Northeastern State 26, Southwestern Okla. 0 | |
| Oct 28, 2000 | Durant, Okla. | Southwestern Okla. 10, Southeastern Okla. 6 | |
| Oct 21, 2000 | Weatherford | Southwestern Okla. 65, Panhandle State 0 | |
| Oct 14, 2000 | Ada, OK | East Central 13, Southwestern Okla. 6 | |
| Oct 07, 2000 | Weatherford | Southwestern Okla. 27, Central Oklahoma 21 | |
| Sep 30, 2000 | Weatherford, Okla | Southwestern Okla. 24, Texas A&M-Commerce 14 | |
| Sep 16, 2000 | Weatherford | Tarleton State 27, Southwestern Okla. 22 | |
| Sep 09, 2000 | Kingsville, Texas | Southwestern Okla. 16, Texas A&M-Kingsville 13 | |
| Sep 02, 2000 | Alamosa, Colo. | Southwestern Okla. 16, Adams State 9 |