| Date | Location | Result | |
| Nov 13, 2010 | Abilene, TX | Abilene Christian 47, Southwestern Okla. 17 | Box score |
| Nov 06, 2010 | Weatherford, OK | Southwestern Okla. 31, Central Oklahoma 24 | Box score |
| Oct 30, 2010 | Weatherford, OK | Texas A&M-Kingsville 56, Southwestern Okla. 17 | Box score |
| Oct 24, 2010 | Commerce, TX | Southwestern Okla. 24, Texas A&M-Commerce 10 | Box score |
| Oct 15, 2010 | Weatherford, OK | Northeastern State 20, Southwestern Okla. 10 | Box score |
| Oct 09, 2010 | Durant, OK | Southeastern Okla. 42, Southwestern Okla. 35 | Box score |
| Oct. 2, 2010 | Weatherford, OK | Southwestern Okla. 21, Eastern New Mexico 10 | Box score |
| Sep 25, 2010 | Ada, OK | East Central 23, Southwestern Okla. 0 | Box score |
| Sep 18, 2010 | Wichita Falls, Texas | Midwestern State 46, Southwestern Okla. 9 | Box score |
| Sep 11, 2010 | Weatherford, OK | West Texas A&M 77, Southwestern Okla. 14 | Box score |
| Aug 26, 2010 | Weatherford, OK | Emporia State 27, Southwestern Okla. 7 | Box score |